Great List from LinuxHaxor

1)  twhirl:
Thanks to Adobe Air deploying applications over multiple platform is easier than ever. twhirl is one of the most widely used twitter desktop clients out there. It supports multiple accounts over multiple social networks with a decent user interface.

2) twitus: A simple GTK+ twitter client with several distribution specific packages.

3) gtwitter: Inspired by twitterrific and written in Mono/C#, this is another good GTK+ based Linux client.

4) Qwit: Native KDE users will appreciate this twitter clients developed with Qt4.

5) Mitter: A light weight python twitter client which can also be also used from the console.

6) Gwibber: Another python based client that supports multiple microblogging network.

7) KickTweet: A simple Kicker applet for KDE.

8)TweetDeck: With more than 1 million active users, this is perhaps the most widely used twitter client available. Installs with Adobe Air.

9) BLT: For the fearless among you, BLT is a pearl scripts that integrates twitter into bash. It updates new tweets into your console which you can reply to from the console.

10) Spaz: A slick Adobe Air client with many option with emphasize on user customization.

Hope

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